Details of antibiotic resistance mechanisms revealed in hospital-acquired drug-resistant pathogens
[2018-03-02] A new paper published by the research groups of Gemma Atkinson and Vasili Hauryliuk at Umeå University resolves years of uncertainty about how the widespread antibiotic resistance factors in the protein group ABCF family confer resistance to lincosamide antibiotics, often used in treatment of infections caused by staphylococci, streptococci and anaerobic bacteria.
Antibiotic resistance is one of the biggest threats to global health, food security, and development today and the new antimicrobial strategies are urgently needed. Scientists at the Umeå Centre for Microbial Research (UCMR) and at The Laboratory for Molecular Infection Medicine Sweden (MIMS) study therefore also antibacterial resistance mechanisms in order to develop new therapeutic strategies against resistant bacteria. The researchers solved recently a mystery in antibiotic resistance research and published their findings in the journal Nucleic Acids Research, which specialises in leading edge research into nucleic acids such as DNA and RNA, and the proteins with which they interact.
