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Publications of MIMS Principle Investigators 2012-2018

From 2012 - August 2018 the MIMS principle investigators published 472 publications in international peer-reviewed journals. 274 publications were published by scientist in MIMS Junior Groups.

pdfComplete publication list (2012-2018)

 Publications of MIMS PIs 2012-2018 (until 2018-09-01)


  1. Abbara A, Rawson TM, Karah N, El-Amin W, Hatcher J, Tajaldin B, Dar O, Dewachi O, Abu Sitta G, Uhlin BE, Sparrow A (2018) Antimicrobial resistance in the context of the Syrian conflict: Drivers before and after the onset of conflict and key recommendations. Int J Infect Dis 73: 1-6
  2. Abbara A, Rawson TM, Karah N, El-Amin W, Hatcher J, Tajaldin B, Dar O, Dewachi O, Sitta GA, Uhlin BE, Sparrow A (2018) Part 1: Antimicrobial resistance in the context of the Syrian conflict: a summary and appraisal of existing evidence. Int J Infect Dis
  3. Åkesson K, Pettersson S, Stahl S, Surowiec I, Hedenström M, Eketjall S, Trygg J, Jakobsson PJ, Gunnarsson I, Svenungsson E, Idborg H (2018) Kynurenine pathway is altered in patients with SLE and associated with severe fatigue. Lupus Sci Med 5: e000254
  4. Alam A, Golovliov I, Javed E, Sjöstedt A (2018) ClpB mutants of Francisella tularensis subspecies holarctica and tularensis are defective for type VI secretion and intracellular replication. Scientific reports 8: 11324
  5. Aliashkevich A, Alvarez L, Cava F (2018) New Insights Into the Mechanisms and Biological Roles of D-Amino Acids in Complex Eco-Systems. Front Microbiol 9: 683
  6. Alvarez L, Aliashkevich A, de Pedro MA, Cava F (2018) Bacterial secretion of D-arginine controls environmental microbial biodiversity. ISME J 12: 438-450
  7. Askarian F, Lapek JD, Jr., Dongre M, Tsai CM, Kumaraswamy M, Kousha A, Valderrama JA, Ludviksen JA, Cavanagh JP, Uchiyama S, Mollnes TE, Gonzalez DJ, Wai SN, Nizet V, Johannessen M (2018) Staphylococcus aureus Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models. Front Microbiol 9: 262
  8. Bacal J, Moriel-Carretero M, Pardo B, Barthe A, Sharma S, Chabes A, Lengronne A, Pasero P (2018) Mrc1 and Rad9 cooperate to regulate initiation and elongation of DNA replication in response to DNA damage. EMBO J
  9. Baggen J, Hurdiss DL, Zocher G, Mistry N, Roberts RW, Slager JJ, Guo H, van Vliet ALW, Wahedi M, Benschop K, Duizer E, de Haan CAM, de Vries E, Casasnovas JM, de Groot RJ, Arnberg N, Stehle T, Ranson NA, Thibaut HJ, van Kuppeveld FJM (2018) Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus. Proceedings of the National Academy of Sciences of the United States of America 115: 397-402
  10. Bamyaci S, Ekestubbe S, Nordfelth R, Erttmann SF, Edgren T, Forsberg A (2018) YopN Is Required for Efficient Effector Translocation and Virulence in Yersinia pseudotuberculosis. Infection and immunity 86
  11. Bergström S, Normark J (2018) Microbiological features distinguishing Lyme disease and relapsing fever spirochetes. Wien Klin Wochenschr 130: 484-490
  12. Charpentier E (2018) Spotlight on... Emmanuelle Charpentier. FEMS Microbiol Lett 365
  13. Codemo M, Muschiol S, Iovino F, Nannapaneni P, Plant L, Wai SN, Henriques-Normark B (2018) Immunomodulatory Effects of Pneumococcal Extracellular Vesicles on Cellular and Humoral Host Defenses. mBio 9
  14. Coquel F, Silva MJ, Techer H, Zadorozhny K, Sharma S, Nieminuszczy J, Mettling C, Dardillac E, Barthe A, Schmitz AL, Promonet A, Cribier A, Sarrazin A, Niedzwiedz W, Lopez B, Costanzo V, Krejci L, Chabes A, Benkirane M, Lin YL et al. (2018) SAMHD1 acts at stalled replication forks to prevent interferon induction. Nature 557: 57-61
  15. Duffy MR, Alonso-Padilla J, John L, Chandra N, Khan S, Ballmann MZ, Lipiec A, Heemskerk E, Custers J, Arnberg N, Havenga M, Baker AH, Lemckert A (2018) Generation and characterization of a novel candidate gene therapy and vaccination vector based on human species D adenovirus type 56. J Gen Virol 99: 135-147
  16. Eneslätt K, Golovliov I, Ryden P, Sjöstedt A (2018) Vaccine-Mediated Mechanisms Controlling Replication of Francisella tularensis in Human Peripheral Blood Mononuclear Cells Using a Co-culture System. Front Cell Infect Microbiol 8: 27
  17. Gupta N, Mohling S, McKendrick R, Elkattah R, Holcombe J, Furr RS, Boren T, DePasquale S (2018) Perioperative outcomes of robotic hysterectomy with mini-laparotomy versus open hysterectomy for uterus weighing more than 250 g. J Robot Surg
  18. Gylfe Å, Ribers A, Forsman O, Bucht G, Alenius GM, Wallberg-Jonsson S, Ahlm C, Evander M (2018) Mosquitoborne Sindbis Virus Infection and Long-Term Illness. Emerging infectious diseases 24: 1141-1142
  19. Hille F, Richter H, Wong SP, Bratovic M, Ressel S, Charpentier E (2018) The Biology of CRISPR-Cas: Backward and Forward. Cell 172: 1239-1259
  20. Hovold G, Palmcrantz V, Kahn F, Egesten A, Pahlman LI (2018) Heparin-binding protein in sputum as a marker of pulmonary inflammation, lung function, and bacterial load in children with cystic fibrosis. BMC Pulm Med 18: 104
  21. Kong Z, Jia S, Chabes AL, Appelblad P, Lundmark R, Moritz T, Chabes A (2018) Simultaneous determination of ribonucleoside and deoxyribonucleoside triphosphates in biological samples by hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry. Nucleic acids research 46: e66
  22. Kudrin P, Dzhygyr I, Ishiguro K, Beljantseva J, Maksimova E, Oliveira SRA, Varik V, Payoe R, Konevega AL, Tenson T, Suzuki T, Hauryliuk V (2018) The ribosomal A-site finger is crucial for binding and activation of the stringent factor RelA. Nucleic acids research 46: 1973-1983
  23. Kulen M, Lindgren M, Hansen S, Cairns AG, Grundstrom C, Begum A, van der Lingen I, Brannstrom K, Hall M, Sauer UH, Johansson J, Sauer-Eriksson AE, Almqvist F (2018) Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes. J Med Chem 61: 4165-4175
  24. Kumar K, Cava F (2018) Integrating network analysis with chromatography: introducing a novel chemometry-chromatography based analytical procedure to classify the bacterial cell wall collection. Analytical Methods 10: 1172-1180
  25. Labuhn M, Adams FF, Ng M, Knoess S, Schambach A, Charpentier EM, Schwarzer A, Mateo JL, Klusmann JH, Heckl D (2018) Refined sgRNA efficacy prediction improves large- and small-scale CRISPR-Cas9 applications. Nucleic acids research 46: 1375-1385
  26. Lanz MC, Oberly S, Sanford EJ, Sharma S, Chabes A, Smolka MB (2018) Separable roles for Mec1/ATR in genome maintenance, DNA replication, and checkpoint signaling. Genes Dev 32: 822-835
  27. Lasswitz L, Chandra N, Arnberg N, Gerold G (2018) Glycomics and Proteomics Approaches to Investigate Early Adenovirus-Host Cell Interactions. J Mol Biol 430: 1863-1882
  28. Lenman A, Liaci AM, Liu Y, Frängsmyr L, Frank M, Blaum BS, Chai W, Podgorski, II, Harrach B, Benko M, Feizi T, Stehle T, Arnberg N (2018) Polysialic acid is a cellular receptor for human adenovirus 52. Proceedings of the National Academy of Sciences of the United States of America 115: E4264-E4273
  29. Li S, Xu Z, Xu J, Zuo L, Yu C, Zheng P, Gan H, Wang X, Li L, Sharma S, Chabes A, Li D, Wang S, Zheng S, Li J, Chen X, Sun Y, Xu D, Han J, Chan K et al. (2018) Rtt105 functions as a chaperone for replication protein A to preserve genome stability. EMBO J 37
  30. Lindqvist R, Kurhade C, Gilthorpe JD, Överby AK (2018) Cell-type- and region-specific restriction of neurotropic flavivirus infection by viperin. J Neuroinflammation 15: 80
  31. Manav MC, Beljantseva J, Bojer MS, Tenson T, Ingmer H, Hauryliuk V, Brodersen DE (2018) Structural basis for (p)ppGpp synthesis by the Staphylococcus aureus small alarmone synthetase RelP. The Journal of biological chemistry 293: 3254-3264
  32. Murina V, Kasari M, Hauryliuk V, Atkinson GC (2018) Antibiotic resistance ABCF proteins reset the peptidyl transferase centre of the ribosome to counter translational arrest. Nucleic acids research 46: 3753-3763
  33. Orrego AH, Lopez-Gallego F, Espaillat A, Cava F, Guisan JM, Rocha-Martin J (2018) One‐step Synthesis of α‐Keto Acids from Racemic Amino Acids by A Versatile Immobilized Multienzyme Cell‐free System. ChemCatChem 10
  34. Panayiotou C, Lindqvist R, Kurhade C, Vonderstein K, Pasto J, Edlund K, Upadhyay AS, Överby AK (2018) Viperin Restricts Zika Virus and Tick-Borne Encephalitis Virus Replication by Targeting NS3 for Proteasomal Degradation. Journal of virology 92
  35. Pena Carcamo JR, Morell ML, Vazquez CA, Vatansever S, Upadhyay AS, Överby AK, Cordo SM, Garcia CC (2018) The interplay between viperin antiviral activity, lipid droplets and Junin mammarenavirus multiplication. Virology 514: 216-229
  36. Peng XP, Lim S, Li S, Marjavaara L, Chabes A, Zhao X (2018) Acute Smc5/6 depletion reveals its primary role in rDNA replication by restraining recombination at fork pausing sites. PLoS genetics 14: e1007129
  37. Quereda JJ, Andersson C, Cossart P, Johansson J, Pizarro-Cerda J (2018) Role in virulence of phospholipases, listeriolysin O and listeriolysin S from epidemic Listeria monocytogenes using the chicken embryo infection model. Vet Res 49: 13
  38. Rajan A, Persson BD, Frängsmyr L, Olofsson A, Sandblad L, Heino J, Takada Y, Mould AP, Schnapp LM, Gall J, Arnberg N (2018) Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells. Scientific reports 8: 10019
  39. Rzhepishevska O, Limanska N, Galkin M, Lacoma A, Lundquist M, Sokol D, Hakobyan S, Sjöstedt A, Prat C, Ramstedt M (2018) Characterization of clinically relevant model bacterial strains of Pseudomonas aeruginosa for anti-biofilm testing of materials. Acta biomaterialia 76: 99-107
  40. Saleeb M, Mojica S, Eriksson AU, Andersson CD, Gylfe A, Elofsson M (2018) Natural product inspired library synthesis - Identification of 2,3-diarylbenzofuran and 2,3-dihydrobenzofuran based inhibitors of Chlamydia trachomatis. European journal of medicinal chemistry 143: 1077-1089
  41. Saleeb M, Sundin C, Aglar O, Pinto AF, Ebrahimi M, Forsberg Å, Schuler H, Elofsson M (2018) Structure-activity relationships for inhibitors of Pseudomonas aeruginosa exoenzyme S ADP-ribosyltransferase activity. European journal of medicinal chemistry 143: 568-576
  42. Surowiec I, Johansson E, Stenlund H, Rantapaa-Dahlqvist S, Bergström S, Normark J, Trygg J (2018) Quantification of run order effect on chromatography - mass spectrometry profiling data. J Chromatogr A 1568: 229-234
  43. Talagrand-Reboul E, Boyer PH, Bergström S, Vial L, Boulanger N (2018) Relapsing Fevers: Neglected Tick-Borne Diseases. Front Cell Infect Microbiol 8: 98
  44. Tsatsaronis JA, Franch-Arroyo S, Resch U, Charpentier E (2018) Extracellular Vesicle RNA: A Universal Mediator of Microbial Communication? Trends Microbiol 26: 401-410
  45. van Mourik PM, de Jong J, Sharma S, Kavsek A, Chabes A, Chang M (2018) Upregulation of dNTP Levels After Telomerase Inactivation Influences Telomerase-Independent Telomere Maintenance Pathway Choice in Saccharomyces cerevisiae. G3 (Bethesda) 8: 2551-2558
  46. Vonderstein K, Nilsson E, Hubel P, Nygard Skalman L, Upadhyay A, Pasto J, Pichlmair A, Lundmark R, Överby AK (2018) Viperin targets flavivirus virulence by inducing assembly of non-infectious capsid particles. Journal of virology 92: e01751-17
  47. Westerberg S, Hagbom M, Rajan A, Loitto V, Persson BD, Allard A, Nordgren J, Sharma S, Magnusson KE, Arnberg N, Svensson L (2018) Interaction of Human Enterochromaffin Cells with Human Enteric Adenovirus 41 Leads to Serotonin Release and Subsequent Activation of Enteric Glia Cells. Journal of virology 92
  48. Yu C, Gan H, Serra-Cardona A, Zhang L, Gan S, Sharma S, Johansson E, Chabes A, Xu RM, Zhang Z (2018) A mechanism for preventing asymmetric histone segregation onto replicating DNA strands. Science


  1. Abraham NM, Liu L, Jutras BL, Yadav AK, Narasimhan S, Gopalakrishnan V, Ansari JM, Jefferson KK, Cava F, Jacobs-Wagner C, Fikrig E (2017) Pathogen-mediated manipulation of arthropod microbiota to promote infection. Proceedings of the National Academy of Sciences of the United States of America 114: E781-E790
  2. Ahsen ME, Boren TP, Singh NK, Misganaw B, Mutch DG, Moore KN, Backes FJ, McCourt CK, Lea JS, Miller DS, White MA, Vidyasagar M (2017) Sparse feature selection for classification and prediction of metastasis in endometrial cancer. BMC Genomics 18: 233
  3. Avican U, Doruk T, Ostberg Y, Fahlgren A, Forsberg Å (2017) The Tat Substrate SufI Is Critical for the Ability of Yersinia pseudotuberculosis To Cause Systemic Infection. Infection and immunity 85
  4. Bagnato P, Castagnino A, Cortese K, Bono M, Grasso S, Bellese G, Daniele T, Lundmark R, Defilippi P, Castagnola P, Tacchetti C (2017) Cooperative but distinct early co-signaling events originate from ERBB2 and ERBB1 receptors upon trastuzumab treatment in breast cancer cells. Oncotarget 8: 60109-60122
  5. Beljantseva J, Kudrin P, Andresen L, Shingler V, Atkinson GC, Tenson T, Hauryliuk V (2017) Negative allosteric regulation of Enterococcus faecalis small alarmone synthetase RelQ by single-stranded RNA. Proceedings of the National Academy of Sciences of the United States of America 114: 3726-3731
  6. Beljantseva J, Kudrin P, Jimmy S, Ehn M, Pohl R, Varik V, Tozawa Y, Shingler V, Tenson T, Rejman D, Hauryliuk V (2017) Molecular mutagenesis of ppGpp: turning a RelA activator into an inhibitor. Scientific reports 7: 41839
  7. Bitar A, De R, Melgar S, Aung KM, Rahman A, Qadri F, Wai SN, Shirin T, Hammarström ML (2017) Induction of immunomodulatory miR-146a and miR-155 in small intestinal epithelium of Vibrio cholerae infected patients at acute stage of cholera. PloS one 12: e0173817
  8. Björnsdottir H, Dahlstrand Rudin A, Klose FP, Elmwall J, Welin A, Stylianou M, Christenson K, Urban CF, Forsman H, Dahlgren C, Karlsson A, Bylund J (2017) Phenol-Soluble Modulin alpha Peptide Toxins from Aggressive Staphylococcus aureus Induce Rapid Formation of Neutrophil Extracellular Traps through a Reactive Oxygen Species-Independent Pathway. Front Immunol 8: 257
  9. Bröms JE, Meyer L, Sjöstedt A (2017) A mutagenesis-based approach identifies amino acids in the N-terminal part of Francisella tularensis IglE that critically control Type VI system-mediated secretion. Virulence 8: 821-847
  10. Castanheira S, Cestero JJ, Rico-Perez G, Garcia P, Cava F, Ayala JA, Pucciarelli MG, Garcia-Del Portillo F (2017) A Specialized Peptidoglycan Synthase Promotes Salmonella Cell Division inside Host Cells. mBio 8
  11. Cava F (2017) Divergent functional roles of D-amino acids secreted by Vibrio cholerae. Int Microbiol 20: 149-150
  12. Cava F (2017) Biology of Vibrio cholera. Editorial overview. Int Microbiol 20: 105
  13. Daste F, Walrant A, Holst MR, Gadsby JR, Mason J, Lee JE, Brook D, Mettlen M, Larsson E, Lee SF, Lundmark R, Gallop JL (2017) Control of actin polymerization via the coincidence of phosphoinositides and high membrane curvature. J Cell Biol 216: 3745-3765
  14. Desvars-Larrive A, Liu X, Hjertqvist M, Sjöstedt A, Johansson A, Ryden P (2017) High-risk regions and outbreak modelling of tularemia in humans. Epidemiol Infect 145: 482-490
  15. Dimova LG, Zlatkov N, Verkade HJ, Uhlin BE, Tietge UJF (2017) High-cholesterol diet does not alter gut microbiota composition in mice. Nutr Metab (Lond) 14: 15
  16. Esberg A, Sheng N, Marell L, Claesson R, Persson K, Boren T, Strömberg N (2017) Streptococcus Mutans Adhesin Biotypes that Match and Predict Individual Caries Development. EBioMedicine 24: 205-215
  17. Gan H, Yu C, Devbhandari S, Sharma S, Han J, Chabes A, Remus D, Zhang Z (2017) Checkpoint Kinase Rad53 Couples Leading- and Lagging-Strand DNA Synthesis under Replication Stress. Molecular cell 68: 446-455 e3
  18. Garzon J, Rodriguez R, Kong Z, Chabes A, Rodriguez-Acebes S, Mendez J, Moreno S, Garcia-Higuera I (2017) Shortage of dNTPs underlies altered replication dynamics and DNA breakage in the absence of the APC/C cofactor Cdh1. Oncogene 36: 5808-5818
  19. Gekara NO (2017) DNA damage-induced immune response: Micronuclei provide key platform. J Cell Biol 216: 2999-3001
  20. Ginley BG, Emmons T, Lutnick B, Urban CF, Segal BH, Sarder P (2017) Computational detection and quantification of human and mouse neutrophil extracellular traps in flow cytometry and confocal microscopy. Scientific reports 7: 17755
  21. Good JAD, Kulen M, Silver J, Krishnan KS, Bahnan W, Nunez-Otero C, Nilsson I, Wede E, de Groot E, Gylfe A, Bergström S, Almqvist F (2017) Thiazolino 2-Pyridone Amide Isosteres As Inhibitors of Chlamydia trachomatis Infectivity. J Med Chem 60: 9393-9399
  22. Gylfe Å, Cajander S, Wahab T, Angelin M (2017) Melioidos: en viktig diagnos vid svår sjukdom efter utlandsresa. Läkartidningen 114
  23. Hansen LM, Gideonsson P, Canfield DR, Boren T, Solnick JV (2017) Dynamic Expression of the BabA Adhesin and Its BabB Paralog during Helicobacter pylori Infection in Rhesus Macaques. Infection and immunity 85
  24. Hauryliuk V, Atkinson GC (2017) Small Alarmone Synthetases as novel bacterial RNA-binding proteins. RNA biology 14: 1695-1699
  25. Ho O, Rogne P, Edgren T, Wolf-Watz H, Login FH, Wolf-Watz M (2017) Characterization of the Ruler Protein Interaction Interface on the Substrate Specificity Switch Protein in the Yersinia Type III Secretion System. The Journal of biological chemistry 292: 3299-3311
  26. Hoernke M, Mohan J, Larsson E, Blomberg J, Kahra D, Westenhoff S, Schwieger C, Lundmark R (2017) EHD2 restrains dynamics of caveolae by an ATP-dependent, membrane-bound, open conformation. Proceedings of the National Academy of Sciences of the United States of America 114: E4360-E4369
  27. Holst MR, Vidal-Quadras M, Larsson E, Song J, Hubert M, Blomberg J, Lundborg M, Landstrom M, Lundmark R (2017) Clathrin-Independent Endocytosis Suppresses Cancer Cell Blebbing and Invasion. Cell reports 20: 1893-1905
  28. Honn M, Lindgren H, Bharath GK, Sjöstedt A (2017) Lack of OxyR and KatG Results in Extreme Susceptibility of Francisella tularensis LVS to Oxidative Stress and Marked Attenuation In vivo. Front Cell Infect Microbiol 7: 14
  29. Howell M, Aliashkevich A, Salisbury AK, Cava F, Bowman GR, Brown PJB (2017) Absence of the Polar Organizing Protein PopZ Results in Reduced and Asymmetric Cell Division in Agrobacterium tumefaciens. Journal of bacteriology 199
  30. Hurwitz JL, Jones BG, Charpentier E, Woodland DL (2017) Hypothesis: RNA and DNA Viral Sequence Integration into the Mammalian Host Genome Supports Long-Term B Cell and T Cell Adaptive Immunity. Viral Immunol 30: 628-632
  31. Ignatov D, Johansson J (2017) RNA-mediated signal perception in pathogenic bacteria. Wiley Interdiscip Rev RNA 8
  32. Jers C, Ravikumar V, Lezyk M, Sultan A, Sjoling A, Wai SN, Mijakovic I (2017) The Global Acetylome of the Human Pathogen Vibrio cholerae V52 Reveals Lysine Acetylation of Major Transcriptional Regulators. Front Cell Infect Microbiol 7: 537
  33. Kable ME, Hansen LM, Styer CM, Deck SL, Rakhimova O, Shevtsova A, Eaton KA, Martin ME, Gideonsson P, Boren T, Solnick JV (2017) Host Determinants of Expression of the Helicobacter pylori BabA Adhesin. Scientific reports 7: 46499
  34. Kajan GL, Kajon AE, Pinto AC, Bartha D, Arnberg N (2017) The complete genome sequence of human adenovirus 84, a highly recombinant new Human mastadenovirus D type with a unique fiber gene. Virus Res 242: 79-84
  35. Karah N, Jolley KA, Hall RM, Uhlin BE (2017) Database for the ampC alleles in Acinetobacter baumannii. PloS one 12: e0176695
  36. Kindstedt E, Holm CK, Sulniute R, Martinez-Carrasco I, Lundmark R, Lundberg P (2017) CCL11, a novel mediator of inflammatory bone resorption. Scientific reports 7: 5334
  37. Kochenova OV, Bezalel-Buch R, Tran P, Makarova AV, Chabes A, Burgers PM, Shcherbakova PV (2017) Yeast DNA polymerase zeta maintains consistent activity and mutagenicity across a wide range of physiological dNTP concentrations. Nucleic acids research 45: 1200-1218
  38. Krajewski SS, Ignatov D, Johansson J (2017) Two Are Better Than One: Dual Targeting of Riboswitches by Metabolite Analogs. Cell Chem Biol 24: 535-537
  39. Krajewski SS, Isoz I, Johansson J (2017) Antibacterial and antivirulence effect of 6-N-hydroxylaminopurine in Listeria monocytogenes. Nucleic acids research 45: 1914-1924
  40. Kudrin P, Varik V, Oliveira SR, Beljantseva J, Del Peso Santos T, Dzhygyr I, Rejman D, Cava F, Tenson T, Hauryliuk V (2017) Subinhibitory Concentrations of Bacteriostatic Antibiotics Induce relA-Dependent and relA-Independent Tolerance to beta-Lactams. Antimicrobial agents and chemotherapy 61
  41. Kumar K, Cava F (2017) Constraint randomised non-negative factor analysis (CRNNFA): an alternate chemometrics approach for analysing the biochemical data sets. Analyst 142: 1916-1928
  42. Kumar K, Espaillat A, Cava F (2017) PG-Metrics: A chemometric-based approach for classifying bacterial peptidoglycan data sets and uncovering their subjacent chemical variability. PloS one 12: e0186197
  43. Le Rhun A, Lecrivain AL, Reimegard J, Proux-Wera E, Broglia L, Della Beffa C, Charpentier E (2017) Identification of endoribonuclease specific cleavage positions reveals novel targets of RNase III in Streptococcus pyogenes. Nucleic acids research 45: 2329-2340
  44. Maciejewska B, Roszniowski B, Espaillat A, Kesik-Szeloch A, Majkowska-Skrobek G, Kropinski AM, Briers Y, Cava F, Lavigne R, Drulis-Kawa Z (2017) Klebsiella phages representing a novel clade of viruses with an unknown DNA modification and biotechnologically interesting enzymes. Appl Microbiol Biotechnol 101: 673-684
  45. Maciejewska B, Zrubek K, Espaillat A, Wisniewska M, Rembacz KP, Cava F, Dubin G, Drulis-Kawa Z (2017) Modular endolysin of Burkholderia AP3 phage has the largest lysozyme-like catalytic subunit discovered to date and no catalytic aspartate residue. Scientific reports 7: 14501
  46. Maicher A, Gazy I, Sharma S, Marjavaara L, Grinberg G, Shemesh K, Chabes A, Kupiec M (2017) Rnr1, but not Rnr3, facilitates the sustained telomerase-dependent elongation of telomeres. PLoS genetics 13: e1007082
  47. Melo AA, Hegde BG, Shah C, Larsson E, Isas JM, Kunz S, Lundmark R, Langen R, Daumke O (2017) Structural insights into the activation mechanism of dynamin-like EHD ATPases. Proceedings of the National Academy of Sciences of the United States of America 114: 5629-5634
  48. Mojica SA, Salin O, Bastidas RJ, Sunduru N, Hedenstrom M, Andersson CD, Nunez-Otero C, Engstrom P, Valdivia RH, Elofsson M, Gylfe A (2017) N-Acylated Derivatives of Sulfamethoxazole Block Chlamydia Fatty Acid Synthesis and Interact with FabF. Antimicrobial agents and chemotherapy 61
  49. Moreno-Guzman M, Garcia-Carmona L, Molinero-Fernandez A, Cava F, Lopez Gil MA, Escarpa A (2017) Bi-enzymatic biosensor for on-site, fast and reliable electrochemical detection of relevant D-amino acids in bacterial samples. Sensors and actuators B, Chemical 242: 95-101
  50. Niemiec MJ, Grumaz C, Ermert D, Desel C, Shankar M, Lopes JP, Mills IG, Stevens P, Sohn K, Urban CF (2017) Dual transcriptome of the immediate neutrophil and Candida albicans BMC Genomics 18: 696
  51. Orikiiriza J, Surowiec I, Lindquist E, Bonde M, Magambo J, Muhinda C, Bergström S, Trygg J, Normark J (2017) Lipid response patterns in acute phase paediatric Plasmodium falciparum malaria. Metabolomics 13: 41
  52. Putzova D, Panda S, Hartlova A, Stulik J, Gekara NO (2017) Subversion of innate immune responses by Francisella involves the disruption of TRAF3 and TRAF6 signalling complexes. Cell Microbiol 19.
  53. Reimer J, Knoss S, Labuhn M, Charpentier EM, Göhring G, Schlegelberger B, Klusmann JH, Heckl D (2017) CRISPR-Cas9-induced t(11;19)/MLL-ENL translocations initiate leukemia in human hematopoietic progenitor cells in vivo. Haematologica 102: 1558-1566
  54. Renault TT, Abraham AO, Bergmiller T, Paradis G, Rainville S, Charpentier E, Guet CC, Tu Y, Namba K, Keener JP, Minamino T, Erhardt M (2017) Bacterial flagella grow through an injection-diffusion mechanism. eLife 6
  55. Richter F, Fonfara I, Gelfert R, Nack J, Charpentier E, Moglich A (2017) Switchable Cas9. Curr Opin Biotechnol 48: 119-126
  56. Schmidt TT, Reyes G, Gries K, Ceylan CU, Sharma S, Meurer M, Knop M, Chabes A, Hombauer H (2017) Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis. Proceedings of the National Academy of Sciences of the United States of America 114: E4442-E4451
  57. Singh B, Mortezaei N, Savarino SJ, Uhlin BE, Bullitt E, Andersson M (2017) Antibodies Damage the Resilience of Fimbriae, Causing Them To Be Stiff and Tangled. Journal of bacteriology 199
  58. Storm RJ, Persson BD, Skalman LN, Frangsmyr L, Lindstrom M, Rankin G, Lundmark R, Domellof FP, Arnberg N (2017) Human Adenovirus Type 37 Uses alphaVbeta1 and alpha3beta1 Integrins for Infection of Human Corneal Cells. Journal of virology 91
  59. Surowiec I, Gouveia-Figueira S, Orikiiriza J, Lindquist E, Bonde M, Magambo J, Muhinda C, Bergström S, Normark J, Trygg J (2017) The oxylipin and endocannabidome responses in acute phase Plasmodium falciparum malaria in children. Malar J 16: 358
  60. Terceti MS, Rivas AJ, Alvarez L, Noia M, Cava F, Osorio CR (2017) rstB Regulates Expression of the Photobacterium damselae subsp. damselae Major Virulence Factors Damselysin, Phobalysin P and Phobalysin C. Front Microbiol 8: 582
  61. Tobias J, Lebens M, Wai SN, Holmgren J, Svennerholm AM (2017) Surface expression of Helicobacter pylori HpaA adhesion antigen on Vibrio cholerae, enhanced by co-expressed enterotoxigenic Escherichia coli fimbrial antigens. Microb Pathog 105: 177-184
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Emmanuelle Charpentier took the Nobel Prize in Chemistry

Emmanuelle has been awarded jointly with Jennifer Doudna the 2020 Nobel Prize in Chemistry for discovering the groundbreaking CRISPR-Cas9 gene editing technology. She is a former group leader at MIMS, honorary doctor at Umeå University and former visiting professor at UCMR.

Movie by Knut and Alice Wallenberg Foundation (

Battling antibiotic resistance

movie by Knut and Alice Wallenberg Foundation, with participation of scientists from MIMS and UCMR:
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Research about infectious diseases:

Oliver Billker in movie of Knut and Alice Wallenberg Foundation:
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