UMU logo

The Swedish Metabolomics Centre (SMC)

The Swedish Metabolomics Centre (SMC; SLU/UmU) is a state-of-the-art facility which is specialized in the use of mass spectrometry based methods for the analysis of metabolites in different biological systems. Dedicated staff offer analysis of samples for a wide range of different research fields, from clinical to plant research. SMC is also a part of the Swedish Science for Life Laboratory SciLifeLab (www.scilifelab.se).

The center has two parts, a service component and a research and development component named ”Metabolomics 2.0”.


SMC performs basically two types of analyses:
1) untargeted metabolite (metabolomics) or lipid profiling by GC-MS and LC-MS;
2) targeted analysis of individual metabolites or metabolite classes with LC-MS or GC-MS (amino acids, fatty acids, TMAO, plant hormones, steroids and others).

The goal is to continuously add more methods to the facility’s service portfolio, with focus on methods of general interest.

SMC performs development of quantitative methods for metabolite analysis in order to offer new targeted methods for future projects.

The centre accepts methodological requests from researchers for specific metabolites with the goal of establishing targeted methods. Following a discussion of the client’s project, the centre carries out a pilot study in order to determine if it is possible to analyze metabolites in the defined biological tissue (matrix) using either LC-MS or GC-MS. These pilot studies are based as much as possible on the existing workflow generally used at SMC (methanol / water or Folch extraction, UHPLC (C18)-ESI-QqQ- or QTOF-detection, alternatively GC-TOF or GC-QqQ detection).

Access to the facility

The Metabolomics facility at Umeå Plant Science is open for the Swedish universities.

 

Funding

The facility is now receiving funding from SLU.  Knut & Alice Wallenberg (KAW) and The Kempe foundation are highly acknowledged for previous funding.

Organisation:

 

Scientific director
Thomas Moritz, professor
UPSC, SLU, Umeå.
Tel: 090-786 84 56; 070 2690684

Scientific Co-director:
Anders Nordström

Contact and Manager:
Jonas Gullberg, PhD
Facility Manager, Swedish Metabolomics Centre
KBC, Umeå University and SLU
901 87 Umeå 
This email address is being protected from spambots. You need JavaScript enabled to view it.
+46 (0)90 786 8393

More information:
www.swedishmetabolomicscentre.se

Chemometrical expertise

Johan Trygg (co-director)
Research group for chemometrics, UmU, Umeå
This email address is being protected from spambots. You need JavaScript enabled to view it.This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Henrik Antti
Research group for chemometrics, UmU, Umeå
This email address is being protected from spambots. You need JavaScript enabled to view it.This e-mail address is being protected from spambots. You need JavaScript enabled to view it


Steering committee
Thomas Moritz, SLU, This email address is being protected from spambots. You need JavaScript enabled to view it.This e-mail address is being protected from spambots. You need JavaScript enabled to view it ,  (Chair)
Johan Trygg, UmU, This email address is being protected from spambots. You need JavaScript enabled to view it.This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Maria Fällman, UmU, This email address is being protected from spambots. You need JavaScript enabled to view it.This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Per Gardeström, UmU, This email address is being protected from spambots. You need JavaScript enabled to view it.This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Stefan Marklund, UmU, This email address is being protected from spambots. You need JavaScript enabled to view it.This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Ove Nilsson, SLU, This email address is being protected from spambots. You need JavaScript enabled to view it.This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Bernt-Eric Uhlin, UmU, This email address is being protected from spambots. You need JavaScript enabled to view it.This e-mail address is being protected from spambots. You need JavaScript enabled to view it

play Webpage of the Metabolomics Patform at UPSC/KBC

Emmanuelle Charpentier:
MIMS is characterized by
ECharpentier about MIMS 2015 1

Emmanuelle Charpentier, Alumna at MIMS, now Director of the Max Planck Unit for the Science of Pathogens and Director of the Department of Regulation in Infection Biology, Max Planck Institute for Infection Biology, Berlin, Germany.

Link to the Emmanuelle Charpentier Lab

footer all slides 2014-02-06


Copyright © 2017 by The Laboratory for Molecular Infection Medicine Sweden (MIMS). All rights reserved.