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Seminar by John Overington webcasted from FIMM to Umeå

EMBL Partnership for Molecular Medicine (FIMM - MIMS - NCMM) joint Special Seminar at the Biomedicum in Helsinki. Video transfer of the talk to Umeå and Oslo simultanously. Speaker: John Overington EMBL Outstation - Hinxton, European Bioinformatics Institute, Cambridge, UK Title:  A data mining synthesis approach to the discovery of impersonalised, robust and safe therapies Abstract: Adverse Drug Reactions, ADRs, are a major burden on healthcare systems, and arguably, if patients can be stratified, more novel therapies, tolerable in particular genotyped groups could be developed and launched. We have taken a data synthesis approach to explore ADRs and some of the underlying molecular recognition and pharmacokinetic concepts. We then derived a novel drug combination strategy which theoretically can greatly improve the safety of current therapies and also lead to more predictable and consistent patient population response. About John Overington Organizer in Sweden: Åke Forsberg Host at FIMM in Finland: Heidi Virtanen Place: Major Groove, Department of Molecular Biology, bldg 6L, University Hospital Area