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PhD-position in Chemistry with focus on Biochemistry

We are now recruiting a PhD student to a project where we study translocation of bacterial proteins, especially in Gram-negative bacteria. The main techniques that we use are structural biology in combination with biochemical methods. The applicant should have experience in biochemistry research and be interested in structural biology. Application deadline is 2018-11-16.

Description
The project involves research on bacterial proteins using structural biology approaches. In particular, the lab uses protein crystallography in combination with biophysical methods and cryo-electron microscopy. This project is focused on a protein machinery that is involved in transportation of proteins from the bacterial inner membrane to the outer. Further, we are interested in the assembly of bacterial surface proteins. Your tasks will include protein purification and characterization, protein crystallization and structure determination using X-ray crystallography. You may also be involved in data acquisition for cryo-electron tomography and single particle cryo-electron microscopy. The group is part of the Umeå Centre for Microbial Research (UCMR) and collaborating with The Laboratory for Molecular Infection Medicine Sweden (MIMS).

Admission requirements
You are required to have completed a second- cycle level degree, or completed course requirements of at least 240 ECTS credits, of which at least 60 ECTS credits are at second-cycle level, or have an equivalent education from abroad, or equivalent qualifications.

To fulfil the specific entry requirements for doctoral studies in chemistry, you are required to have completed first-cycle courses of at least 90 ECTS credits within the field of chemistry or another subject considered to be directly relevant to the specialization in question. Of those 90 ECTS credits, at least 15 ECTS credits shall have been acquired at second-cycle level within the specialization or an equivalent subject.

Good knowledge in English, both written and spoken, is required. Experience in research related to biochemistry, achieved through for example a diploma work at advanced level in a research group or similar, is a requirement. You should have a keen interest in the project, like experimental work, be precise, and be able to work both independently and in a group. Prior experience in membrane protein biochemistry is an advantage but not a priority.

About the position
The position is intended to result in a doctoral degree and the main task of the PhD student is to pursue their doctoral studies which include both participation in research and postgraduate courses. The duties can include teaching and other departmental work (up to a maximum of 20%). Employment is limited to four years of full-time or up to five years for teaching part time. Salary is set in accordance with the established salary ladder for PhD position.

Application
A complete application should contain the following documents:

  • A cover letter including a description of your research interests, your reasons to apply for the position, and your contact information
  • A curriculum vitae
  • A copy of completed BSc and/or MSc thesis and, if applicable, other research publications
  • Certified copies of degree certificates, including documentation of completed academic courses and obtained grades and other relevant certificates
  • Contact information of at least two reference persons

The application should be written in Swedish or English. Applications must be submitted via our recruiting system. The last day to apply is November 16, 2018.

For more information please contact Karina Persson, phone: +46-90-7865926, email: This email address is being protected from spambots. You need JavaScript enabled to view it.

www.biostruct.umu.se/principal-investigators/karina-persson/

Information about the department
The Department of Chemistry is one of the largest departments in the Faculty of Science and Technology, with about 200 employees, including about 40 doctoral students, and a strong and expanding research. Three major areas of research; Biological Chemistry, Environmental and Biogeochemistry and Technical Chemistry, represents the research and chemistry education of our department. We are also a strong partner in KBC, The Chemical-Biological Centre. Information about the postgraduate education can be found on the Faculty of Science and Technology website: http://www. teknat.umu.se/english/doctoral-studies/. For more information about working at Umeå University: https://www.umu.se/en/work-with-us/

Emmanuelle Charpentier:
MIMS is characterized by
ECharpentier about MIMS 2015 1

Emmanuelle Charpentier, Alumna at MIMS, now Director of the Max Planck Unit for the Science of Pathogens and Director of the Department of Regulation in Infection Biology, Max Planck Institute for Infection Biology, Berlin, Germany.

Link to the Emmanuelle Charpentier Lab

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