In the group of Björn O. Schröder at The Laboratory for Molecular Infection Medicine Sweden (MIMS), the Swedish partner within the Nordic EMBL Partnership for Molecular Medicine, new Postdoc opportunities are available. The laboratory is located in the Department for Molecular Biology at Umeå University, Sweden.
To prevent infection by or translocation of the gut microbiota into underlaying tissues, the intestinal epithelium exhibits defense mechanisms, such as the production of intestinal mucus and antimicrobial peptides (AMPs). Our research projects will focus on how dietary and other factors influence the interaction between gut microbiota and the mucosal barrier (intestinal mucus and AMPs) and we will investigate the relevance of this interaction in the context of diseases, such as inflammatory bowel disease and metabolic diseases.
In the laboratory we will use a combination of gut microbiota analyses, microbiota transplantations (FMT), state-of-the-art ex vivo mucus measurements, antimicrobial assays, as well as confocal and fluorescence microscopy. In addition, we will use dietary interventions in mice and humans and closely work with Norrlands University Hospital Umeå (NUS) to analyze relevant patient samples.
Successful candidates must hold a university degree (PhD or equivalent for postdoctoral applications) in a subject area relevant for the positions. Furthermore, applicants for a postdoctoral position should have experience in mucosal barrier function and/or gut microbiota research and must have good knowledge of standard molecular biology and biochemical methods. For all candidates, working experience with mouse studies, gut microbiota analyses + manipulations and/or imaging techniques are strong merits.
Successful candidates need to be highly motivated, have very good communication skills and are expected to be at ease collaborating with other scientists. They should have high capacity to independently organize and lead projects. International experience is a merit while good skills in both oral and written communication in English is a must. Great emphasis will be placed on personal suitability.