Master thesis projects available in advanced molecular biology protocol development, of relevance for CAR T cells and malaria high-throughput screening! Hard working students who are prepared to roll up their sleeves and move out of their comfort zone are most welcome to apply :)
We are developing several protocols to improve the efficiency of pooled CRISPR or barseq screens, where extracting more information about each cell will boost the statistics. This is especially important when the cells are few (primary cells) or the expansion is uneven (in vivo screens). The project may also be combined with bioinformatics (python, R or java) based on student interests.
Keywords: Cloning, sequencing, inverse PCR, padlock probes, UMIs, mate pairing, HiC, ATACseq, RNAseq, CRISPR, cell culture, lentiviruses, bioinformatics
Illustration by Johan Henriksson.
You don't need to be a biologist if you are interested in computing sciences and or mathematics and interested in systems biology or statistics, you will get a very good opportunity to learn from Johan Henriksson at MIMS. We like to model biology through equations. Do you want to help us? Summer projects/thesis options/etc possible.
Go to www.henlab.org for more information. Find out more about Johan Henriksson on http://www.mims.umu.se/groups/johan-henriksson.html