Regulated release of membrane vesicles from the human pathogen Group A streptococcus
[2016-11-14] Release of vesicles from the outer membrane are known to play an important role in the biology of Gram-negative bacteria. They are relevant for pathogenesis and interaction of the bacteria with their environment. Only recently was it observed that membrane vesicles (MVs) also can be released from Gram-positive bacteria which lack an outer membrane and have a thick cell wall. The composition and mechanisms which govern the MV formation in Gram-positive bacteria was still unclear. Now, a new study, published in mBio, a high impact journal of the American Society for Microbiology, shows new findings on the composition and the regulation of MVs production in the Gram-positive, human pathogen, Group A streptococcus.