Exosome-like bacterial membrane vesicles containing RNA – “Bactexomes”
New findings reveal a hitherto unrecognised feature of bacterial membrane vesicles that are mimicking eukaryotic exosomes and contain RNA that can be delivered to host tissues and cells. Professor Sun Nyunt Wai and colleagues at MIMS and Department of Molecular Biology, Umeå University, are reporting that RNA can be found in bacterial membrane vesicles. This discovery highlights the potential role of RNA-containing bacterial membrane vesicles to be involved in bacteria-host interactions.
The findings are published in the latest issue of Scientific Reports-Nature Publishing Group.
Authors are Annika Sjöström, Linda Sandblad, Bernt Eric Uhlin, Sun Nyunt Wai.
Annika E. Sjöström, Linda Sandblad, Bernt Eric Uhlin & Sun Nyunt Wai (2015): Membrane vesicle-mediated release of bacterial RNA. Scientific Reports 5:15329; DOI: 10.1038/srep15329. Published Online 2015-10-20.
Picture: Cryo-electron tomogram of purified vesicles. Original published in Scientific Reports.