Two projects at Umeå University receive funding in international collaborations with the aim to stop antimicrobial resistant bacteria

MIMS and UCMR Researchers are funded by the Swedish Research Council for their participation in International research collaborations in two research consortia funded within the European Joint Programming Initiative on Antimicrobial Resistance (JPIAMR). These are the only pojects that are funded in Sweden in this call.

[2018-10-30] MIMS Group Leader and UCMR Researcher Vasili Hauryliuk, Department of Molecular Biology, is part of the project “Development of novel ribosome-targeting antibiotics” with collaborators in Germany, France, Czech Republic and Italy. Under the lead of Daniel Wilson at the University of Hamburg, Germany, the collaborating laboratories will focus on discovering novel antibiotics which are targeted towards the ribosome, the cellular protein fabric, which is one of the major target of existing antibiotics.

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MIMS Mini-Symposium Fall 2018

Welcome to the MIMS  Mini-Symposium in Molecular Infection Medicine Fall 2018!

Tuesday, 30 October 2018, 9:00 - 12:00
Venue: Lecture hall E04, Biomedicine Building, Norrland University Hospital, Unod R1 (map for download here)

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Expert in genomics of human immune disorders recruited as new Director of NCMM

Congratulations from MIMS to Janna Saarela to her apointment as new Director of our partner institute in Norway!
[2018-10-12] The University of Oslo has recruited Dr Janna Saarela, Research Director of Institute for Molecular Medicine Finland (FIMM), the Finnish node of the Nordic EMBL Partnership, as the new Director of Centre for Molecular Medicine Norway (NCMM).

"We congratulate our partner institute in Oslo to the appointment of an excellent scientist and competent leader. We look forward to work closely with Janna Saarela and her leadership team through the Nordic EMBL Partnership", commented MIMS Director Oliver Billker the good news from the NCMM.

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SEK 30 million grant for malaria parasite research at MIMS

[20181004] The Knut and Alice Wallenberg Foundation grants Oliver Billker, professor and newly appointed director of  The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, SEK 30 million to study gene functions of malaria parasites.

"I am very grateful for this support. It is through this kind of generous and long-term funding that we will be able to ask big questions and to bring in the new technologies that we need to answer them," says Oliver Billker, who has recently been recruited as a professor of biotechnology at Umeå University.

"Our research wants to better understand the biology of malaria parasite in order to find new strategies against malaria, a disease that causes enormous suffering in the world, especially in countries with fewer financial resources and poor healthcare," says Oliver Billker.

Read more: SEK 30 million grant for malaria parasite research at MIMS

Nitrite’s got to be cruel to be kind

The Cholera pathogen uses a smart metabolic switch to control population expansion and survival for an optimal adaptation to the intestine’s low-oxygen environments.

The human pathogen Vibrio cholerae has puzzled the scientists since its discovery 150 years ago. Experts who studied the bacterium couldn’t understand that the bacterium was not able to grow under anaerobic conditions despite it was equipped with an active metabolic machinery which should enable the organism to respire nitrate instead of oxygen, conditions that typically exist in the gastrointestinal tract. The common opinion was that the bacteria accumulates the intermediate product nitrite which inhibits further growth.

The research group of Felipe Cava at The Laboratory for Molecular Infection Medicine Sweden studied this bacteria now under low-oxygen and different pH-conditions. Together with their colleagues in Boston, USA, the scientists at Umeå University discovered an elegant pH-dependent metabolic mechanism which permits the pathogen to switch to a resting mode with preserved viability. A smart strategy that provides competitive advantage against commensal bacteria to better colonize and infect the intestine. The group published the results now in the latest issue of Nature Microbiology 1 October 2018.

Read more: Nitrite’s got to be cruel to be kind