Treatment of cancer could become possible with adenovirus
[2018-04-19] An international team of researchers led by professor Niklas Arnberg at Umeå University, shows that adenovirus binds to a specific type of carbohydrate that is overexpressed on certain types of cancer cells. The discovery opens up new opportunities for the development of virus-based cancer therapy. The study is published in the latest issue of the scientific journal "Proceedings of the National Academy of Sciences of USA", PNAS April 19, 2018.
Adenovirus is a common virus that causes infectious diseases of the respiratory tract, eyes and gastrointestinal tract in humans and animals. Researchers at Umeå University study molecular mechanisms of infection in order to understand how adenovirus causes disease.
The researchers in Umeå, together with research groups from Germany, the UK and Hungary, have now discovered a new type of mechanism used by a rare adenovirus type to attack cells.