Please note: In connection with the KBC Research School course "What you need to know to be effective in writing and publishing your work", 13-17 May 2013, the instructor will also give a seminar at KBC:
EMG and IceLab Seminar
Speaker: Michael E. Hochberg Institute of Evolutionary Sciences, University of Montpellier II France
Title: Cancer as an ecological and evolutionary process
Department of Medical Biochemistry and Biophysics Seminar Series 2013
Speaker: David Gally Division of Immunity and Infection, The Roslin Institute, University of Edinburgh
Title: New moronic behaviour and Stx appeal
Room: KB3A9, Lilla hörsalen KBC Host: Matthew Francis
Abstract: The seminar will introduce the different pathotypes of E. coli and focus on infections associated with Shiga toxin (Stx) producing E. coli (STEC). The talk will cover published information on the potential advantages that Stx may provide for E. coli colonising the main reservoir host (ruminants) and then will discuss our recent research examining how both protein and sRNA regulators present on integrated bacteriophages can alter host strain phenotype or ‘behaviour’. Overall, the talk covers how the horizontal acquisition of different phage-encoded ‘morons’1 (‘More’ DNA or more ‘ome’) is driving the evolution of Stx-encoding E. coli strains in cattle with serious consequences for humans as an incidental host.
1Juhala et al (2000) Genomic sequences of bacteriophages HK97 and HK022: pervasive genetic mosaicism in the lambdoid bacteriophages. J Mol Biol 299:27-51.
Speaker: Samuel Miller Professor of Medicine, Microbiology, Immunology and Genome Sciences at the University of Washington, U.S.A.
Title: c-di-GMP and bacterial cellular diversity
Caroline Zetterström will defend her thesisi June 7 with Prof. Miller as faculty opponent. In the afternoon the same day as the defense Prof. Miller will give a seminar. Web: http://miller-lab.net/MillerLab/ Samuel I. Miller is a Professor of Medicine, Microbiology, Immunology and Genome Sciences at the University of Washington. He has been the Director of the NIAID Northwest Research Center for Excellence in Biodefense and Emerging Infectious Diseases since its inception in 2003 and of the University of Washington Enteric Research Investigative Center of NIAID since 2010. He is the past Director of the Cystic Fibrosis Research and Development Program at the U W. He received his B.A. from John Hopkins University in 1975 and M.D. in 1979 from Baylor College of Medicine and was an Intern, Resident, Fellow, Assistant and Associate Professor at the Massachusetts General Hospital and Harvard Medical School. His research training was in the laboratories of Dr. Dyann Wirth (Harvard School of Public Health, molecular parasitiology) and Dr. John Mekalanos (Harvard Medical School, bacterial pathogenesis).
Room: KB3B1, Stora hörsalen KBC Host. Mikael Elofsson