Double seminar 14:00-16:00 in Betula with complimentary coffee break Speaker1: Uwe Tietge University Medical Center Groningen, The Netherlands Title: Regulation of reverse cholesterol transport Host: Stefan K. Nilsson, MedBio
Speaker 2: Brian English Howard Hughes Medical Institute, USA Title: Insights into mRNA compartmentalization and translation by simultaneous single particle tracking of ribosomes and mRNAs, and by super-resolution imaging of cytoskeletal structures in live cells
Speaker: Rohan Davis Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, Australia
Title: Natural Product Drug Discovery @ Eskitis
Place: Lilla hörsalen, KB3A9
Host: Mikael Elofsson
Abstract: Abstract: Nature has continuously provided the human race with a broad and structurally diverse arsenal of pharmacologically active compounds that have been effectively utilised in the treatment of numerous diseases. More than 50% of all marketed drugs in the world are natural products or their derivatives. Well-known examples of valuable natural products used as medicines today include tacrolimus (immunosuppressant), erythromycin (antibiotic), paclitaxel (breast/ovarian/lung cancer), lovastatin (cholesterol lowering) and galantamine (anti-Alzheimer). Due to the developing resistance of many cancer-types, microbes and parasites, and the minimal safety and efficacy associated with certain drugs on the market today, there is still a high demand for the discovery and development of new therapeutics. This talk will detail current biodiscovery efforts being undertaken by the Davis research group at the Eskitis Institute, Griffith University.
Biosketch: Dr. Rohan Davis obtained his Bachelor of Science (Hons) from the University of Melbourne in 1992, with co-majors in organic chemistry and biochemistry. Rohan worked as a research assistant on the AstraZeneca/Griffith University Biodiscovery Program (1994–1996) before undertaking his doctoral studies (1997–2000) at Griffith University in the area of marine organic chemistry under the supervision of Prof. Ron Quinn and Prof. Tony Carroll, A post-doctoral stint at the University of Utah with Prof. Chris Ireland was undertaken (2001–2003) before returning to Griffith to set up his research group, which currently focuses on the identification and synthesis of bioactive natural products from plants, fungi and marine invertebrates. This research has resulted in the discovery of many new compounds, some of which have been shown to display potent anti-cancer, anti-bacterial and/or anti-malarial activity. Dr. Davis has authored 91 publications in international chemistry/biology journals, and currently holds one patent.
One Health Sweden started out as The Infection Ecology and Epidemiology network in Uppsala 2010 by Uppsala University, the National Veterinary Institute (SVA), the Swedish University of Agricultural Sciences (SLU) and the Linnaeus University (Kalmar). The idea was to stimulate interdisciplinary collaborations with potential to increase knowledge of the emergence, spread and effects of infectious diseases and antibiotic resistance in humans, domestic animals and wildlife. One Health Sweden provides a platform for cross-disciplinary collaboration and exchange of ideas, representing the width of zoonotic infection research, from wildlife ecology to advanced microbiology (www.onehealth.se).
Umeå is a centre for excellent infection biology research and we would like to meet people interested in infectious diseases and antibiotic resistance in general, and the One Health approach in particular. Therefore we want to invite to a meeting where coordinators from Uppsala shortly inform about the network and Hanna Söderström, Dept. of Chemistry, Umeå University, gives a talk about the One Health Sweden project on development of resistance in avian influenza viruses to antiviral drugs followed by discussions with focus on new collaborations.
This invitation has been sent to Umeå University, University Hospital of Norrland (Umeå), Swedish Defense Research Agency (FOI) and Swedish University of Agricultural Sciences (SLU).
Date: Thursday 7th Nov 2013 Time: 15.00-17.00 (fika will be served around 16) Place: Umeå University, KBC building, KB3A9 lilla hörsalen
For further information and registration, please contact any of us.
National and International Seminar Series 2013 Speaker: Martin Hällberg Cell and molecular biology, Karolinska Institute, Sweden and Center for Structural Systems Biology, DESY Campus, Hamburg, Germany