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Welcome to the new lab of Bjoern O. Schroeder!

181019 GSO Portraits9505 562 Christopher Coe

Started April 2019

 

PI: Bjoern O. Schroeder, Ph.D.
Department of Molecular Biology
Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.

 

To prevent infection by or translocation of the gut microbiota into underlaying tissues, the intestinal epithelium exhibits defense mechanisms, such as the production of intestinal mucus and antimicrobial peptides (AMPs). Our research projects will focus on how dietary and other factors influence the interaction between gut microbiota and the mucosal barrier (intestinal mucus and AMPs) and we will investigate the relevance of this interaction in the context of diseases, such as inflammatory bowel disease and metabolic diseases.

In the laboratory we will use a combination of gut microbiota analyses, microbiota transplantations (FMT), state-of-the-art ex vivo mucus measurements, antimicrobial assays, as well as confocal and fluorescence microscopy. In addition, we will use dietary interventions in mice and humans and closely work with Norrlands University Hospital Umeå (NUS) to analyze relevant patient samples.In the Schröder lab we are interested to better understand the close relationship between host and microbes in the intestine. Specifically, we focus on antimicrobial peptides, which are host-produced peptide antibiotics, and intestinal mucus, the gel-like layer that is covering the intestinal epithelium. We use a combination of gut microbiota analyses, microbiota transplantations (FMT), state-of-the-art ex vivo mucus measurements, antimicrobial assays, as well as confocal and fluorescence microscopy. In addition, we use dietary interventions in mice and humans and will closely work with Norrlands University Hospital Umeå (NUS) to analyze relevant patient samples.

Our new lab is at the Department of Molecular Biology, which is located on the Campus of the University Hospital of Umeå (Norrlands universitetssjukhus).


Our new lab is recruiting!

Postdoctoral candidates, PhD students and undergraduate students (Summer/ Bachelor-/ Master level) who are interested, are welcome to contact Björn Ole Schröder, This email address is being protected from spambots. You need JavaScript enabled to view it..

More information about Bjoern Schroeder's lab: https://mucubacter.org/


 

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