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Postdoc position in autophagy and chemo-optogenetics at UCMR and KBC, Umeå University

We are looking for an ambitious postdoc to work on an ERC-funded project on autophagy and chemo-optogenetics. The fellowship is funded by the Knut and Alice Wallenberg Foundation (KAW). The project is interdisciplinary with strong collaborations across scientific disciplines. 
For information about project details, qualifications and how to apply for the postdoctoral fellowship, please see the advertisement:
https://www.nature.com/naturecareers/job/postdoctoral-fellow-autophagy-and-chemooptogenetics-umea-university-umu-732619
Application deadline; 1 Feb 2021.

Postdoc opportunity in the Urban lab

Two-year postdoc opportunity up for grabs in the Urban lab at Umeå University, Department of Clinical Microbiology

Picture1 Constantin UProject: We are an internationally leading research group interested in innate immunity in bacterial and fungal infections. The current project aims at elucidating fundamental cellular mechanisms in neutrophils which regulate metal ion fluxes and how these processes contribute to antimicrobial activities of these phagocytes. We use sophisticated methodologies such as high-resolution X-ray fluorescence, spinning disk microscopy, ICP mass spectrometry, and whole genome transcriptional profiling using RNA-Seq.

Come and join a motivated and energetic team in the beautiful North of Sweden!  Continue reading for more details about this opportunity.

Image credit: C. Urban, MIMS-UCMR. Heatmap from X-ray fluorescent experiment showing element distribution of zinc (Zn), sulfur (S) and potassium (K) in neutrophil (PMN) engulfing yeast.

Read more: Postdoc opportunity in the Urban lab

Post-doc positions in the Hauryliuk lab

Hauryliuk postdoc 2020 21

Postdoctoral Research Opportunity in Infection Biology at Umeå University, Sweden

Project: The type VI secretion system of Francisella tularensis 

PI: Anders Sjöstedt

The aim is to delineate the regulation of assembly and the functions of the components of the Type VI secretion systems (T6SS) of Francisella tularensis (Ft). Ft encodes an atypical T6SS, which allows this highly virulent, intracellular bacterium to invade and replicate within the cytosol of eukaryotic cells and the T6SS is thereby essential for Ft virulence. While T6SSs have been the focus of an intense research effort for over a decade, our understanding is still incomplete regarding many of the functions of T6SSs in general and that of Ft in particular.

The research will be carried out by generating specific mutants and constructs encoding tagged T6SS components. These will then be tested by a variety of techniques, including several microscopic techniques, to detect the localization and secretion of the proteins, as well as their protein interaction partners. One focus will be on the baseplate, the foundation on which the external part of the machinery rests. Detailed structural knowledge is very limited regarding the Ft baseplate, a consequence of the low sequence identity between Ft T6SS components and those of prototypic T6SSs. We are currently conducting detailed analysis by means of for example two-hybrid interaction analysis, immunoprecipitation, ascorbate peroxidase 2 (APEX)-tagging, and confocal and electron microscopy methods. 

Application deadline: 7 January 2021. Continue to read for all details and how to apply. 

Read more: Postdoctoral Research Opportunity in Infection Biology at Umeå University, Sweden

PostDoc position in whole brain imaging

A post doc position is available for highly motivated candidates. The project focuses on visualizing viral infection and pathological changes in whole mouse brain. By developing and using advanced 3D imaging methods we want to answer how neurotropic flaviviruses gain access to the brain and cause disease. The project will be conducted in the group of Anna K Överby at The Laboratory for Molecular Infection Medicine Sweden (MIMS), the Swedish node of the Nordic EMBL Partnership for Molecular Medicine at Umeå University and Department of Clinical Microbiology, Umeå University.

Application deadline: 18 December 2020. To see the full job description and to apply, please go to:

 

PhD/PostDoc Opportunities - Molecular Infection Biology and Cell-Autonomous Immunity

IF280720 Slc1 new WT B 2 cropProject: Many of the most significant pathogens have the capacity to invade human cells and to exploit the interior of their host cell as replicative niche. While human cells have powerful defense programs that can restrict the growth of such invaders, successful pathogens typically evolved to resist these attacks. In the Sixt Lab, we believe that a profound understanding of the molecular basis of this arms race could pave the way for innovative therapeutics that can fight pathogens by unleashing the host cell-intrinsic defenses. Specifically, we strive to explore cell-autonomous immunity and evasion mechanisms during infection with the obligate intracellular bacterial pathogen Chlamydia trachomatis, and we seek ways to manipulate the balance to the benefit of the host.

We are currently seeking a PostDoc and a PhD student for a project that will apply state-of-the-art tools in molecular genetics, microscopy, and high-throughput genetic screening to determine the role of the Chlamydia-containing vacuole in counteracting cell-autonomous immunity.

Credit for image: Barbara Sixt, MIMS, Umeå University. Human cell infected with Chlamydia trachomatis.

Continue to read for all details on how to apply!

Read more: PhD/PostDoc Opportunities - Molecular Infection Biology and Cell-Autonomous Immunity

Postdoc Fellowship on mouse fertilization, mouse gamete interactions by cryo-ET at Umeå University and Karolinska Institute

Welcome to apply for a postdoc fellowship and join our EM community at Umeå University!
You will be studying mouse fertilization, mouse gamete interactions by using cryo-ET and other imaging methods. More information about the overall context of this research, may be found at http://jovinelab.org" data-sk="tooltip_parent">http://jovinelab.org.

The research project is a collaboration between a research group at Karolinska Institutet (KI), Huddinge, Sweden and a research group at the Department of Chemistry, Umeå University, Sweden, associated with the UCEM and Molecular Infection Medicine Sweden (MIMS). The postdoc will be located at the Department of Chemistry, Umeå University and short visits at the KI partner laboratory will be included.

Read more: Postdoc Fellowship on mouse fertilization, mouse gamete interactions by cryo-ET at Umeå University...

The Schröder lab is recruiting

In the group of Björn O. Schröder at The Laboratory for Molecular Infection Medicine Sweden (MIMS), the EMBL Nordic Node at Umeå University, Sweden,  one opportunity for a PhD student or postdoctoral researcher and several opportunities for highly motivated and talented students (Master or Rotation) are available. The laboratory is located in the Department for Molecular Biology at Umeå University.

For details, please go to https://mucubacter.org/jobs/ . 

Interested candidates are welcome to contact Björn Schröder for more information and/or send a letter of interest as one .pdf file in English to This email address is being protected from spambots. You need JavaScript enabled to view it., including: (i) a cover letter, summarizing specific motivation and qualifications that are relevant for this position, (ii) a curriculum vitae, (iii) publication list and (iv) the contact information of two to three references
before Oct 31st , 2020.

Emmanuelle Charpentier took the Nobel Prize in Chemistry

Emmanuelle has been awarded jointly with Jennifer Doudna the 2020 Nobel Prize in Chemistry for discovering the groundbreaking CRISPR-Cas9 gene editing technology. She is a former group leader at MIMS, honorary doctor at Umeå University and former visiting professor at UCMR.

Movie by Knut and Alice Wallenberg Foundation (https://kaw.wallenberg.org/)

MIMS is characterized by
ECharpentier about MIMS 2015 1

Emmanuelle Charpentier, Alumna at MIMS, Director of the Max Planck Unit for the Science of Pathogens, Berlin, Germany.

Link to the Emmanuelle Charpentier Lab

Battling antibiotic resistance

movie by Knut and Alice Wallenberg Foundation, with participation of scientists from MIMS and UCMR:
Or watch the original movie on:
https://kaw.wallenberg.org/

Research about infectious diseases:

Oliver Billker in movie of Knut and Alice Wallenberg Foundation:
Or watch the original movie on:
https://kaw.wallenberg.org/

Emmanuelle Charpentier
about her research at MIMS

footer all slides 2014-02-06


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