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Introduction to high throughput screening - 2 ECTS

Introduction to high throughput screening - 2 ECTS

The course gives a broad introduction to high throughput screening (HTS) that is technique used to identify biologically active small organic molecules through screening of compound libraries with the help of robust test systems and advanced instrumentations.

Participants can start at any time and study in their own paces since the course is entirely web-based with English course material consisting of text, figures, video lectures, review articles, and movies. The students study at their own places and examination will be carried out on request.


Read more: Introduction to high throughput screening - 2 ECTS

Candida albicans escapes from mouse neutrophils - publication of the Constantin Urban lab

Constantin Urban and his colleagues compared the interactions of C. albicans with neutrophil granulocytes from mice and humans. Their studies show that the human immune system is better to cope with fungal infections than the corresponding cells in mice, which are commonly used as a model to study fungal infections.

Press release from Umeå University (in Swedish)

Original publication in Journal of Leucocyte Biology
(Published online before print May 6, 2013, doi: 10.1189/jlb.0213063)

Editorial: Of Mice and Men—Yet Again, by Henry Rosén
(Published in doi:10.1189/jlb.0413187 August 2013, Journal of Leukocyte Biology vol. 94, no. 2: 210-212).

Webpage of Constantin Urban's lab "Antifungal Immunity"

Biomolecular NMR - A hands-on PhD course (2 ECTS)

Biomolecular NMR - A hands-on PhD course (2ECTS)

Organised by the NMR for Life at University of Gothenburg and Umeå University

Venue: Swedish NMR Centre, University of Gothenburg
Dates: 14-­‐18 Oct 2013
Target group: PhD students and researchers with projects involving protein characterization by NMR


• Vladislav Orekhov, Swedish NMR Centre, Univ. of Gothenburg
• Martin Billeter, Chem. and Mol. Biology, Univ. of Gothenburg
• Gerhard Gröbner, Umeå University, Sweden

Information: will be posted at

: by e-­‐mail to orov 'at';  deadline -­‐ 1 Oct 2013; registration fee -­‐ none; number of participants is limited

Read more: Biomolecular NMR - A hands-on PhD course (2 ECTS)

Welcome to the MIMS UCMR Mini-Symposium 30th Sept 2013!

Place: Betula salen, building 6M, University Hospital Area

Welcome to interesting afternoon! Meet new post-docs and group leaders
The post-docs recruited through the first UCMR_MIMS call and the new MIMS group leaders will present their research. Bernt Eric Uhlin director of MIMS and UCMR will give an update over the newest developments at MIMS.

pdfFinal programme for download

Read more: Welcome to the MIMS UCMR Mini-Symposium 30th Sept 2013!

New Group leaders at MIMS

New MIMS group leaders:  Vasili Hauryliuk and Felipe Cava

vasili-hauryliuk 140From the beginning of this summer two additional excellent scientists are setting up their laboratories at MIMS, affiliated to the Department of Molecular Biology at Umeå University.
Vasili Hauryliuk, who most recently was a group leader and assistant professor at the University of Tartu in Estonia, will continue his research on the bacterial stringent response. He combines both experimental and in silico approaches to study the response of microorganisms to environmental stress. Stringent respons is involved in the regulation of bacterial virulence, antibiotic tolerance and biofilm formation. Better understanding of this adaptation of microorganisms is important for the development of specific inhibitors and new antimicrobial strategies.

Read more on the webpage of Vasili Hauryliuk

Felipe CavaBefore Felipe Cava joined MIMS, he was group leader and assistant professor at the Universidad Autonóma de Madrid in Spain. From 2013 he is, after nomination by Umeå University, one of the first Wallenberg Academy Fellows, in the long-term programme for young researchers funded by the Knut and Alice Wallenberg Foundation. Felipe Cava's research area is a very aggressive and original line focused on the diversity and plasticity of bacterial cell walls (primarily made of the murein exoskeleton) under environmental conditions, a topic of the highest relevance to properly understand bacterial relations with neighbouring organisms at all levels, from commensalism to pathogenesis.

Read more on the webpage of Felipe Cava


Carl-Henrik Heldin new Chairman of the Board of the Nobel Foundation

The board of directors of The Nobel Foundation elected at their annual meeting in May 2013 Carl-Henrik Heldin as new chairperson of the Board of the Nobelfoundation. MIMS congratulates Carl-Henrik Heldin for this new position and is very grateful that he also the chair of the MIMS Board.

Professor Hansson. Vice Chairman of the Board says in the press release of the Nobel Foundation:
“We are pleased that Carl-Henrik Heldin will become the new Chairman of the Nobel Foundation’s Board of Directors.( ...) Professor Heldin is one of Scandinavia’s most distinguished scientists and a world authority in molecular biology and cancer research. I am convinced that with his good reputation and high integrity, Carl-Henrik Heldin will do an outstanding job for the Nobel Prize”.

See the whole press release here

25 million SEK for a project to study and inhibit bacterial virulence

Infection research in Umeå will receive considerable funding from the Swedish Council for Strategic Research (SSF). Within the SSF programme Molecular mechanisms in the interplay between microorganisms/parasites and their hosts (man, domestic animals, plants and forest trees) in relation to disease, nine research projects will be supported with a total of SEK 225 million, one project is hosted by Umeå University. Under the leadership of Mikael Elofsson a joint project with Karolinska institute will receive SEK 25 million over the next five years. From Umeå is also Åke Forsberg involved in the project which will focus on substances to study and inhibit bacterial virulence.

Fredrik Almqvist is co-applicant in a second project lead by Birgitta Henriques-Normark, professor at Karolinska Institute in Stockholm and Linnaeus Visiting Professor at UCMR.

Read more in the press release on Umeå University's web page (in Swedish)

Read the press release from SSF (in Swedish)

Iain Mattaj: Honory Doctor at the Faculty of Medicine

web110531 MIMS launch 190Iain MattajIain Mattaj is one of the two honory doctors of the Faculty of Medicine in 2013!

Iain Mattaj is the driving force behind the establishment of the Nordic EMBL Partnership for Molecular Medicine, with MIMS as the Swedish partner, the faculty says in its press release.

Iain Mattaj has played an important role also in the founding of MIMS with his support and advice for the recruitment of young MIMS group leaders.

Iain Mattaj visited Umeå several times and last time he was one of the invited speakers at the launch event for MIMS in 2011.

Read the whole press release in Swedish here:

Picture: Iain Mattaj at the MIMS launch event on 31 May 2011 in Umeå (picture by Marie Andersson)

Revealing the weapons by which bacteria fight each other: NATURE paper by Sun Nyunt Wai and colleagues

Vibrio cholerae biofilm copyright SNWai

Revealing the weapons by which bacteria fight each other

[2013-04-04] A new study which was performed jointly at Umeå University and the University of Washington in Seattle, USA, discovered that bacteria can degrade the cell membrane of bacterial competitors with enzymes that do not harm their own membrane. This exciting finding opens the way for the development of new antibacterial drugs to fight bacteria using their own weapons. (NATURE, 2013, DOI 10.1038/nature12074).

Read more: Revealing the weapons by which bacteria fight each other: NATURE paper by Sun Nyunt Wai and...

MIMS welcomes DANDRITE as new partner in the Nordic EMBL Partnership

DANDRITE, The Danish Research Institute of Translational Neuroscience, is the fourth Nordic partner in The Nordic EMBL Partnership for Molecular Medicine. On March 5th a delegation from MIMS and Umeå University participated in the ceremony at Aarhus University to celebrate the official opening of DANTRITE together with representatives from EMBL and from the nodes and universities in Finland and Norway, FIMM at Helsinki University and NCMM at University of Oslo.

Dandrite inauguration2Signed the new agreement of the Nordic EMBL Partnership for Molecular Medicine in Aarhus (from left to right):
Prof Poul Nissen, director for DANDRITE and Aarhus University,  prof Thomas Wilhelmsson, Rector University of Helsinki, prof Lena Gustafsson, Vice-Chancellor Umeå University, Director General prof Iain Mattaj, EMBL, prof Lauritz B. Holm-Nielsen, Aarhus University, prof Ole Petter Ottersen, University of Oslo, and the directors for the three other Nordic partner nodes prof Olli Kallioniemi, (FIMM), prof Bernt Eric Uhlin (MIMS) and prof Kjetil Taskén (NCMM).

Read more: MIMS welcomes DANDRITE as new partner in the Nordic EMBL Partnership

Battling antibiotic resistance

movie by Knut and Alice Wallenberg Foundation, with participation of scientists from MIMS and UCMR:
Or watch the original movie on:

Research about infectious diseases:

Oliver Billker in movie of Knut and Alice Wallenberg Foundation:
Or watch the original movie on:

footer all slides 2014-02-06

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