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France celebrates Emmanuelle Charpentier during the L'Oreal-UNESCO week in Paris

France Inter[2016-03-24] The L'Oréal Foundation and UNESCO organise a week with media and scientific meetings for the five laureates of the 2016 L'Oréal- UNESCO For Women in Science Awards in the field of Life Sciences. The French woman Emmanuelle Charpentier is a quested person by the French media, giving TV and radio interviews, meeting the press, and also the scientists and students ath the Académie des Sciences. The L'Oreal organised a media marathon for the laureates which represent five continents: From Latin America, Andrea Gmarnik is honored for her discoveries on mosquito-borne viruses, particularly Dengue Fever. From Asia/Pacific the awardee is Hualan Chen, Chinese Academy of Agricultural Sciences, Harbin, China, honored for her research about the bird flu virus, which lead to development of vaccine. Abdool Karim, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, South Africa, represents Africa and the Arab states and is honored for her "remarkable contribution to the prevention and treatment of HIV and associated infections".

ARTEEmmanuelle Charpentier, representing Europe, is awarded "for her game-changing discovery,(...), of a versatile DNA editing technique to “rewrite” flawed genes in people and other living organisms, opening tremendous new possibilities for treating, even curing, diseases." Which is the same motivation as for Jennifer Doudna, who is the fifth women representing North-America. Nominated by more than 2600 leading scientists, a jury, chaired by Nobel Laureate Elizabeth Blackburn, selected this year's laureates. The Prize Ceremony is held on Thursday, 24 March at the Sorbonne in Paris.

More information about the 2016 L'Oreal-UNESCO For Women in Science Award in Life Science

Canadian Gairdner Award to Emmanuelle Charpentier

[2016-03-23] The Gairdner Foundation is awarding Emmanuelle Charpentier and four other scientists with the Gairdner International Award 2016, Canada's most prestigious medical award.

The laureates will be awarded in October during a visit in Canada to speak with faculty and students at 20 universities in the country. The Canada Gairdner International Award is given to "biomedical scientists who have made original contributions to medicine resulting in increased understanding of human biology and disease". Each award is valued $ 100,000 CDN, supported by the Canadian government. Emmanuelle Charpentier is honored "for development of CRISPR-CAS as a genome editing tool for eukaryotic cells".

Read more on the webpage of  the Gairdner Foundation

New compounds discovered as possible candidates for new antimicrobial drugs against Listeria infection

Hep cells grown without and with 2 pyridones

 

Scientists at Umeå Centre for Microbial Research (UCMR) have discovered chemical compounds which are able to attenuate the virulence of the bacterial human pathogen Listeria monocytogenes. Their findings are published today in the high impact journal Cell Chemical Biology.

The dramatic increase of antibiotic resistance makes new antimicrobial strategies necessary. The researchers at Umeå University in Sweden are studying an alternative approach, to inhibit the disease capacity (virulence) of bacteria but not their viability. Compared with traditional antibiotics, which often kill the bacteria, the risk of resistance development in disarmed bacteria is lower, since their survival does not depend on resistance against the new drug.

A Listeria infection can be very severe, particularly among patients such as elderly, infants, immunocompromised or pregnant women. Although disease occurrence is relatively low, Listeria’s severe and sometimes fatal health consequences make it among the most serious foodborne infections, with a mortality of 30%. Listeria is found in unpasteurized dairy products and various ready-to-eat foods, and can grow at refrigeration temperatures. In Sweden, 60-90 people per year get infected and the statistics show that the number of outbreaks is increasing.

The study involved several different Umeå University research groups with diverse specialties: Microbiology, Chemistry and Structural Biology. The group of Jörgen Johansson, professor at the laboratory for Molecular Infection Medicine Sweden (MIMS) and the Department of Molecular Biology collaborated with the research groups of Elisabeth Sauer-Eriksson and Fredrik Almqvist, both professors at the Department of Chemistry.

Read more: New compounds discovered as possible candidates for new antimicrobial drugs against Listeria...

Paul Ehrlich- und Ludwig Darmstaedter Preis 2016 for Emmanuelle Charpentier

[2016-01-25] The Paul Ehrlich Foundation at the Goethe University in Frankfurt am Main, Germany, announced that Emmanuelle Charpentier will receive the Paul Ehrlich- und Ludwig Darmstaedter-Preis 2016 on Paul Ehrlich's birthday, March 14th, at the St. Paul Church in Frankfurt. The Ehrlich Prize is among the most prestigious awards, which are presented to international scientists in Germany in the field of medicine.

The prize honors scientists who have acquired merits in one of the research fields of Paul Ehrlich especially immunology, cancer research, hematology, microbiology and chemotherapy.

play Press release of the Paul Ehrlich Foundation (in German)

Emmanuelle Charpentier awarded "Chevalier de la Légion d’Honneur"

By a presidential decree on December 31, 2015, the French President of the Republic, François Hollande, awarded Emmanuelle Charpentier with the title of "Chevalier de la Légion d’Honneur".
The Légion d’Honneur is the highest French decoration and one of the most famous in the world; it is awarded to people who, by their accomplishments, contribute to the progress of France.

Read more: Emmanuelle Charpentier awarded "Chevalier de la Légion d’Honneur"

CRISPR - Science's Breakthrough of the Year 2015!

CRISPR fig3 250 Linnea Ljung HolmstromThe visitors of Science's website voted for the favorite from a short list of candidates in the People's Choice poll.

Read about the Runners-up stories, the CRISPR revolution topic page with links to featured publications and related article list.

Listen to the AAAS podcast in which the Science editors discuss the breakthrough and the other nine favorite stories of the year 2015.

Link to the journal Science of 17 December 2015 online

 Illustration of CRISPR-Cas9 by Linnea-Ljung Holmström

Emmanuelle Charpentier appointed as Vallee Visiting Professor 2016

"The Vallee Visiting Professorship (VVP) programme pairs outstanding scientists with premier biomedical research institutes worldwide in an informal arrangement that promotes intellectual exchanges and fosters new partnerships" (webpage of the Vallee Foundation).

The motivation on the Foundation's website: "With her recent ground-breaking findings in the field of RNA-mediated regulation based on the CRISPR-Cas9 system, Charpentier has laid the foundation for the development of a novel, highly versatile and specific genome editing technology that is revolutionizing life sciences research and could open up whole new opportunities in biomedical gene therapies."
More information about the Valee Foundation and ite Visting Professorship programme
Read more about the background of the Vallee Foundation (American Society for Biochemistry and Molecular Biology)

Emmanuelle Charpentier appointed as Vallee Visiting Professor 2016

"The Vallee Visiting Professorship (VVP) programme pairs outstanding scientists with premier biomedical research institutes worldwide in an informal arrangement that promotes intellectual exchanges and fosters new partnerships" (webpage of the Vallee Foundation).

The motivation on the Foundation's website: "With her recent ground-breaking findings in the field of RNA-mediated regulation based on the CRISPR-Cas9 system, Charpentier has laid the foundation for the development of a novel, highly versatile and specific genome editing technology that is revolutionizing life sciences research and could open up whole new opportunities in biomedical gene therapies."
More information about the Valee Foundation and the Visting Professorship programme
Read more about the background of the Vallee Foundation (American Society for Biochemistry and Molecular Biology)

Emmanuelle Charpentier awarded the Leibniz Prize 2016

[20151210] Emmanuelle Charpentier is one of the 10 scientists in German who were awarded the Leibniz Prize 2016 by the German Research Organisation, Deutsche Forschungsgemeinschaft (DFG).
She will receive the award on March 1st, 2016. "The Gottfried Wilhelm Leibniz Prize Programme, was established in 1985, aims to improve the working conditions of outstanding researchers, expand their research opportunities, relieve them of administrative tasks, and help them employ particularly qualified early career researchers. A maximum of €2.5 million is provided per award". (webpage of the DFG)

Press release of the Max Planck Society (in German)

Andrea Puhar- Wallenberg Academy Fellow 2015!

Puhar Andrea 8989 151127 MPNwebpage[2015-12-03] Andrea Puhar, new group leader at MIMS, is one of the 29 Wallenberg Academy Fellows 2015. The Knut and Alice Wallenberg Foundation announced in its press release this morning the new Fellows. Andrea Puhar is together with Nasim Sabouri, Department of Medical Biochemistry and Biophysics, the second Fellow to be selected within the Faculty of Medicine at Umeå University, which will host 5 of the 29 new Fellows.
After Felipe Cava, who became Academy Fellow in 2012, Andrea Puhar is the second MIMS group leader who is part of the Foundations "program to support some of Sweden’s – and the world’s – most promising young researchers within humanities, medicine, natural sciences, social science and engineering sciences", as the Foundation says in its press release.

Press release of the Knut and Alice Wallenberg Foundation

Webpage of Andrea Puhar's lab

Press release of Umeå Unversity (in Swedish)

Battling antibiotic resistance

movie by Knut and Alice Wallenberg Foundation, with participation of scientists from MIMS and UCMR:
Or watch the original movie on:
https://kaw.wallenberg.org/

Research about infectious diseases:

Oliver Billker in movie of Knut and Alice Wallenberg Foundation:
Or watch the original movie on:
https://kaw.wallenberg.org/

footer all slides 2014-02-06


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